Impact of left ventricular geometry on prognosis in hypertensive patients with left ventricular hypertrophy (the LIFE study) | Zendy

Eva Gerdts | Zendy; Dana Cramariuc | Zendy; Giovanni de Simone | Zendy; Kristian Wachtell | Zendy; B. Dahlöf | Zendy; R.B. Devereux | Zendy

Open Access

Impact of left ventricular geometry on prognosis in hypertensive patients with left ventricular hypertrophy (the LIFE study)

Author(s) -

Eva Gerdts,

Dana Cramariuc,

Giovanni de Simone,

Kristian Wachtell,

B. Dahlöf,

R.B. Devereux

Publication year - 2008

Publication title -

european journal of echocardiography

Language(s) - English

Resource type - Journals

eISSN - 1525-2167

pISSN - 1532-2114

DOI - 10.1093/ejechocard/jen155

Subject(s) - medicine , cardiology , losartan , atenolol , left ventricular hypertrophy , myocardial infarction , clinical endpoint , stroke (engine) , muscle hypertrophy , blood pressure , randomized controlled trial , angiotensin ii , mechanical engineering , engineering

Less is known about the relation between in-treatment left ventricular (LV) geometry and risk of cardiovascular events. We assessed LV geometric patterns on baseline and annual echocardiograms as time-varying predictors of the primary composite endpoint (cardiovascular death, stroke, and myocardial infarction) in 937 hypertensive patients with LV hypertrophy during 4.8 years losartan- or atenolol-based treatment in the Losartan Intervention for Endpoint reduction in hypertension (LIFE) echocardiography substudy.

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