Locally different proteome in aortas from patients with stenotic tricuspid and bicuspid aortic valves† | Zendy

Amalia Forte | Zendy; Xiaoke Yin | Zendy; Marika Fava | Zendy; Ciro Bancone | Zendy; Marilena Cipollaro | Zendy; Marisa De Feo | Zendy; Manuel Mayr | Zendy; Marjan Jahangiri | Zendy; Alessandro Della Corte | Zendy

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Locally different proteome in aortas from patients with stenotic tricuspid and bicuspid aortic valves†

Author(s) -

Amalia Forte,

Xiaoke Yin,

Marika Fava,

Ciro Bancone,

Marilena Cipollaro,

Marisa De Feo,

Manuel Mayr,

Marjan Jahangiri,

Alessandro Della Corte

Publication year - 2019

Publication title -

european journal of cardio-thoracic surgery

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.303

H-Index - 133

eISSN - 1873-734X

pISSN - 1010-7940

DOI - 10.1093/ejcts/ezz032

Subject(s) - proteome , bicuspid aortic valve , ascending aorta , proteomics , aortic valve , protein expression , biology , tandem mass spectrometry , pathogenesis , aorta , chemistry , microbiology and biotechnology , pathology , medicine , mass spectrometry , biochemistry , immunology , chromatography , gene

We aimed to compare the intracellular proteome of ascending aortas from patients with stenotic bicuspid (BAV) and tricuspid aortic valves (TAV) to identify BAV-specific pathogenetic mechanisms of aortopathy and to verify the previously reported asymmetric expression of BAV aortopathy [concentrated at the convexity (CVX)] in its 'ascending phenotype' form.

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