Is central lung tumour location really predictive for occult mediastinal nodal disease in (suspected) non-small-cell lung cancer staged cN0 on 18F-fluorodeoxyglucose positron emission tomography–computed tomography? | Zendy

Herbert Decaluwé | Zendy; Johnny Moons | Zendy; Steffen Fieuws | Zendy; Walter De Wever | Zendy; Christophe M. Deroose | Zendy; Alessia Stanzi | Zendy; Lieven Depypere | Zendy; Kristiaan Nackaerts | Zendy; Johan Coolen | Zendy; Maarten Lambrecht | Zendy; Eric Verbeken | Zendy; Dirk De Ruysscher | Zendy; Johan Vansteenkiste | Zendy; Dirk Van Raemdonck | Zendy; Paul De Leyn | Zendy; Christophe Dooms | Zendy

Open Access

Is central lung tumour location really predictive for occult mediastinal nodal disease in (suspected) non-small-cell lung cancer staged cN0 on 18F-fluorodeoxyglucose positron emission tomography–computed tomography?

Author(s) -

Herbert Decaluwé,

Johnny Moons,

Steffen Fieuws,

Walter De Wever,

Christophe M. Deroose,

Alessia Stanzi,

Lieven Depypere,

Kristiaan Nackaerts,

Johan Coolen,

Maarten Lambrecht,

Eric Verbeken,

Dirk De Ruysscher,

Johan Vansteenkiste,

Dirk Van Raemdonck,

Paul De Leyn,

Christophe Dooms

Publication year - 2018

Publication title -

european journal of cardio-thoracic surgery

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.303

H-Index - 133

eISSN - 1873-734X

pISSN - 1010-7940

DOI - 10.1093/ejcts/ezy018

Subject(s) - medicine , occult , positron emission tomography , radiology , lung cancer , tomography , positron emission tomography computed tomography , computed tomography , lung , fluorodeoxyglucose , nuclear medicine , pathology , alternative medicine

Current guidelines recommend preoperative invasive mediastinal staging in centrally located tumours with negative mediastinum on positron emission tomography-computed tomography, based on a 20-30% prevalence of occult mediastinal disease (pN2-3). However, a uniform definition of central tumour location is lacking. Our objective was to determine the best definition in predicting occult pN2-3.

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