Open AccessImpact of induction therapy on postoperative outcome after extrapleural pneumonectomy for malignant pleural mesothelioma: does induction-accelerated hemithoracic radiation increase the surgical risk?
Author(s) -
Pierre Mordant,
Karen McRae,
John Cho,
Shaf Keshavjee,
Thomas K. Waddell,
Ronald Feld,
Marc de Perrot
Publication year - 2016
Publication title -
european journal of cardio-thoracic surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.303
H-Index - 133
eISSN - 1873-734X
pISSN - 1010-7940
DOI - 10.1093/ejcts/ezw074
Subject(s) - extrapleural pneumonectomy , medicine , induction chemotherapy , mesothelioma , common terminology criteria for adverse events , surgery , radiation therapy , adverse effect , blood transfusion , pneumonectomy , lung cancer , pathology
Patients with malignant pleural mesothelioma (MPM) eligible for extrapleural pneumonectomy (EPP) may benefit from induction chemotherapy (CT) as historically described, or from induction-accelerated hemithoracic intensity-modulated radiation therapy (IMRT) as a potential alternative. However, the impact of the type of induction therapy on postoperative morbidity and mortality remains unknown.
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