Decellularized fresh homografts for pulmonary valve replacement: a decade of clinical experience | Zendy

Samir Sarikouch | Zendy; Alexander Horke | Zendy; I. Tudorache | Zendy; Philipp Beerbaum | Zendy; Mechthild WesthoffBleck | Zendy; Dietmar Boethig | Zendy; Repin Oleg | Zendy; Maniuc Liviu | Zendy; Anatol Ciubotaru | Zendy; Axel Haverich | Zendy; Serghei Cebotari | Zendy

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Decellularized fresh homografts for pulmonary valve replacement: a decade of clinical experience

Author(s) -

Samir Sarikouch,

Alexander Horke,

I. Tudorache,

Philipp Beerbaum,

Mechthild WesthoffBleck,

Dietmar Boethig,

Repin Oleg,

Maniuc Liviu,

Anatol Ciubotaru,

Axel Haverich,

Serghei Cebotari

Publication year - 2016

Publication title -

european journal of cardio-thoracic surgery

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.303

H-Index - 133

eISSN - 1873-734X

pISSN - 1010-7940

DOI - 10.1093/ejcts/ezw050

Subject(s) - decellularization , medicine , surgery , biomedical engineering , tissue engineering

Decellularized homografts have shown auspicious early results when used for pulmonary valve replacement (PVR) in congenital heart disease. The first clinical application in children was performed in 2002, initially using pre-seeding with endogenous progenitor cells. Since 2005, only non-seeded, fresh decellularized allografts have been implanted after spontaneous recellularization was observed by several groups.

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