Open AccessSafety and efficacy of miniaturized extracorporeal circulation when compared with off-pump and conventional coronary artery bypass grafting: evidence synthesis from a comprehensive Bayesian-framework network meta-analysis of 134 randomized controlled trials involving 22 778 patients
Author(s) -
Mariusz Kowalewski,
Wojciech Pawliszak,
Giuseppe Maria Raffa,
Pietro Giorgio Malvindi,
Magdalena Ewa Kowalkowska,
Katarzyna Zaborowska,
Janusz Kowalewski,
Giuseppe Tarelli,
David P. Taggart,
Lech Anisimowicz
Publication year - 2015
Publication title -
european journal of cardio-thoracic surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.303
H-Index - 133
eISSN - 1873-734X
pISSN - 1010-7940
DOI - 10.1093/ejcts/ezv387
Subject(s) - bypass grafting , extracorporeal circulation , randomized controlled trial , artery , meta analysis , medicine , bayesian network , grafting , cardiology , computer science , materials science , artificial intelligence , composite material , polymer
Coronary artery bypass grafting (CABG) remains the standard of care in patients with extensive coronary artery disease. Yet the use of cardiopulmonary bypass (CPB) is believed to be a major determinant of perioperative morbidity. Novel techniques are sought to tackle the shortcomings of CPB, among them off-pump coronary artery bypass (OPCAB) and miniaturized extracorporeal circulation (MECC) systems have been extensively tested in randomized controlled trials (RCTs). To assess perioperative safety and efficacy of MECC and OPCAB when compared with conventional extracorporeal circulation (CECC).
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