Open AccessImmunotherapy for non-small cell lung cancer: current concepts and clinical trials
Author(s) -
Marissa Mayor,
Neng Yang,
Daniel H. Sterman,
David R. Jones,
Prasad S. Adusumilli
Publication year - 2015
Publication title -
european journal of cardio-thoracic surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.303
H-Index - 133
eISSN - 1873-734X
pISSN - 1010-7940
DOI - 10.1093/ejcts/ezv371
Subject(s) - immunotherapy , medicine , lung cancer , monoclonal antibody , clinical trial , blockade , immunotoxin , cancer , oncology , cancer immunotherapy , immunology , immune system , antibody , receptor
Recent successes in immunotherapeutic strategies are being investigated to combat cancers that have less than ideal responses to standard of care treatment, such as non-small-cell lung cancer. In this paper, we summarize concepts and the current status of immunotherapy for non-small cell lung cancer, including salient features of the major categories of immunotherapy-monoclonal antibody therapy, immune checkpoint blockade, immunotoxins, anticancer vaccines, and adoptive cell therapy.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom