Statin initiation and acute kidney injury following elective cardiovascular surgery: a population cohort study in Denmark | Zendy

J. Bradley Layton | Zendy; Malene Kærslund Hansen | Zendy; Carl-Johan Jakobsen | Zendy; Abhijit V. Kshirsagar | Zendy; Jan Jesper Andreasen | Zendy; Vibeke E. Hjortdal | Zendy; Bodil Steen Rasmussen | Zendy; Ross J. Simpson | Zendy; M. Alan Brookhart | Zendy; Christian Fynbo Christiansen | Zendy

Open Access

Statin initiation and acute kidney injury following elective cardiovascular surgery: a population cohort study in Denmark

Author(s) -

J. Bradley Layton,

Malene Kærslund Hansen,

Carl-Johan Jakobsen,

Abhijit V. Kshirsagar,

Jan Jesper Andreasen,

Vibeke E. Hjortdal,

Bodil Steen Rasmussen,

Ross J. Simpson,

M. Alan Brookhart,

Christian Fynbo Christiansen

Publication year - 2015

Publication title -

european journal of cardio-thoracic surgery

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.303

H-Index - 133

eISSN - 1873-734X

pISSN - 1010-7940

DOI - 10.1093/ejcts/ezv246

Subject(s) - medicine , acute kidney injury , statin , cohort , cardiac surgery , confidence interval , population , surgery , cohort study , cardiology , environmental health

Acute kidney injury (AKI) is a serious complication of cardiac surgery. Statins may prevent post-surgical AKI, yet methodological concerns about existing studies raise questions about the magnitude of a protective effect. We sought to determine the effect of initiating a statin prior to elective cardiac surgery on post-surgical AKI in a regional Danish surgical cohort.

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