Prognostic significance of cancer within 1 mm of the circumferential resection margin in oesophageal cancer patients following neo-adjuvant chemotherapy†‡ | Zendy

Tamir Salih | Zendy; Paul Jose | Zendy; Samir Mehta | Zendy; A. H. MIRZA | Zendy; Gavin Udall | Zendy; Susan Pritchard | Zendy; Jeremy D. Hayden | Zendy; Heike I. Grabsch | Zendy

Open Access

Prognostic significance of cancer within 1 mm of the circumferential resection margin in oesophageal cancer patients following neo-adjuvant chemotherapy†‡

Author(s) -

Tamir Salih,

Paul Jose,

Samir Mehta,

A. H. MIRZA,

Gavin Udall,

Susan Pritchard,

Jeremy D. Hayden,

Heike I. Grabsch

Publication year - 2012

Publication title -

european journal of cardio-thoracic surgery

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.303

H-Index - 133

eISSN - 1873-734X

pISSN - 1010-7940

DOI - 10.1093/ejcts/ezs331

Subject(s) - medicine , cancer , chemotherapy , lymph node , resection margin , esophageal cancer , oncology , adjuvant , surgical margin , multivariate analysis , lymph , gastroenterology , surgery , resection , pathology

The prognostic significance of the circumferential resection margin (CRM) status in oesophageal cancer patients treated with neo-adjuvant chemotherapy and radical resection is controversial. Furthermore, it is currently unclear whether patients with cancer located at the CRM have a prognosis different from that of those with cancer within 1 mm of the CRM. This is the first study aiming to establish the optimal tumour-free distance from the CRM of an oesophagectomy in patients who have undergone neo-adjuvant chemotherapy.

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