Comparison of clinical non-commercial tools for automated quantification of myocardial blood flow using oxygen-15-labelled water PET/CT | Zendy

Hendrik J. Harms | Zendy; С. В. Нестеров | Zendy; Chengzong Han | Zendy; Ibrahim Danad | Zendy; Remi M Leonora | Zendy; Pieter G. Raijmakers | Zendy; Adriaan A. Lammertsma | Zendy; Juhani Knuuti | Zendy; Paul Knaapen | Zendy

Open Access

Comparison of clinical non-commercial tools for automated quantification of myocardial blood flow using oxygen-15-labelled water PET/CT

Author(s) -

Hendrik J. Harms,

С. В. Нестеров,

Chengzong Han,

Ibrahim Danad,

Remi M Leonora,

Pieter G. Raijmakers,

Adriaan A. Lammertsma,

Juhani Knuuti,

Paul Knaapen

Publication year - 2013

Publication title -

european heart journal - cardiovascular imaging

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.576

H-Index - 92

eISSN - 2047-2412

pISSN - 2047-2404

DOI - 10.1093/ehjci/jet177

Subject(s) - cardiac pet , positron emission tomography , coronary artery disease , blood flow , medicine , nuclear medicine , cad , radiology , biomedical engineering , cardiology , chemistry , biochemistry

Absolute quantification of myocardial blood flow (MBF) with (15)O-water cardiac positron emission tomography (PET)/CT has recently demonstrated to hold promising diagnostic value for the detection of coronary artery disease (CAD). However, methodological differences in utilized analysis software packages (SP) could affect generated MBF values, potentially prohibiting widespread clinical applicability of obtained normal thresholds. The aim of this study was to compare two validated non-commercial SP, Carimas and Cardiac VUer, for the quantification of MBF using (15)O-water PET.

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