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Contrast echocardiography reveals apparently normal coronary perfusion in a rat model of stress-induced (Takotsubo) cardiomyopathy
Author(s) -
Björn Redfors,
Yangzhen Shao,
Johannes Wikström,
Alexander R. Lyon,
Anders Oldfors,
LiMing Gan,
Elmir Ömerovic
Publication year - 2013
Publication title -
european heart journal - cardiovascular imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.576
H-Index - 92
eISSN - 2047-2412
pISSN - 2047-2404
DOI - 10.1093/ehjci/jet079
Subject(s) - perfusion , cardiology , medicine , basal (medicine) , pathophysiology , myocardial infarction , cardiomyopathy , heart failure , insulin
Stress-induced cardiomyopathy (SIC) is an important differential diagnosis to acute myocardial infarction (AMI) that is associated with significant morbidity and mortality. The typical hallmark of SIC is left-ventricular apical akinesia but preserved function in basal segments. Catecholamines are postulated to play an important role in SIC but the precise pathophysiology is incompletely understood. Whether myocardial perfusion of the affected segments is impaired in SIC has been debated and remains unknown.

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