Nutrition meets heredity: a case of RNA-mediated transmission of acquired characters
Author(s) -
Minoo Rassoulzadegan,
François Cuzin
Publication year - 2018
Publication title -
current zoology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.971
H-Index - 38
eISSN - 2058-5888
pISSN - 1674-5507
DOI - 10.1093/eep/dvy006
Subject(s) - heredity , epigenetics , inheritance (genetic algorithm) , biology , genetics , mechanism (biology) , gene , disease , rna , medicine , philosophy , epistemology
RNA-based inheritance provides a reasonable hypothesis to explain multigenerational maintenance of the disease in the progeny of either a male or female parent suffering from the metabolic syndrome (obesity and type 2 diabetes) induced by abnormal diet. Although, it is still difficult to formulate a complete rational mechanism, study of inheritance is a most direct way to learn about the epigenetic control of gene expression and we wished to summarised our current approach along this line.
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