Viruses and esophageal cancer | Zendy

Carolyn Chang | Zendy; Stephanie G. Worrell | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Viruses and esophageal cancer

Author(s) -

Carolyn Chang,

Stephanie G. Worrell

Publication year - 2020

Publication title -

diseases of the esophagus

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.115

H-Index - 63

eISSN - 1442-2050

pISSN - 1120-8694

DOI - 10.1093/dote/doaa036

Subject(s) - medicine , esophageal cancer , disease , esophageal adenocarcinoma , incidence (geometry) , adenocarcinoma , herpes simplex virus , virus , cancer , pathogenesis , obesity , oncology , virology , physics , optics

Summary Esophageal adenocarcinoma (EAC) has had the fastest increasing incidence of any solid tumor in the United States in the last 30 years. Long standing gastroesophageal reflux disease is a well-established risk factor with strong associations with obesity, alcohol and tobacco. However, there are likely additional contributing factors. Viruses such as human papillomavirus, ebstein-barr virus and herpes simplex virus have been implicated in the pathogenesis of esophageal cancer. This review will discuss the known literature linking viruses to esophageal adenocarcinoma and consider future relationships such as identifying prognostic and predictive molecular biomarkers to guide therapies.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research