Organization of the Chicken Histone Genes in a Major Gene Cluster and Generation of an Almost Complete Set of the Core Histone Protein Sequences
Author(s) -
Yasuoki Takami
Publication year - 1996
Publication title -
dna research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.647
H-Index - 98
eISSN - 1756-1663
pISSN - 1340-2838
DOI - 10.1093/dnares/3.2.95
Subject(s) - biology , cosmid , histone , genetics , histone h1 , histone h4 , gene , histone h2a , gene cluster , histone methylation , histone h3 , histone code , nucleosome , gene expression , dna methylation
We present a detailed picture of the disposition of the histone genes in the chicken genome and an almost complete set of the core histone protein sequences. Thirty-nine histone genes, six H1, nine H2A, eight H2B, eight H3 and eight H4, were located within a histone gene cluster of 110 kb, which was covered by five cosmid clones and two lambda clones. Results of our sequence analyses, together with those reported previously, generated a set of the core histone amino acid sequences as follows: three H2A variants, four H2B variants, two H3 variants and an H4 protein.
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