CircFunBase: a database for functional circular RNAs | Zendy

Xianwen Meng | Zendy; Dahui Hu | Zendy; Peijing Zhang | Zendy; Qi Chen | Zendy; Ming Chen | Zendy

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CircFunBase: a database for functional circular RNAs

Author(s) -

Xianwen Meng,

Dahui Hu,

Peijing Zhang,

Qi Chen,

Ming Chen

Publication year - 2019

Publication title -

database

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.406

H-Index - 62

ISSN - 1758-0463

DOI - 10.1093/database/baz003

Subject(s) - context (archaeology) , computational biology , genome , computer science , genome browser , circular rna , biology , microrna , genomics , genetics , gene , paleontology

Increasing evidence reveals that circular RNAs (circRNAs) are widespread in eukaryotes and play important roles in diverse biological processes. However, a comprehensive functionally annotated circRNA database is still lacking. CircFunBase is a web-accessible database that aims to provide a high-quality functional circRNA resource including experimentally validated and computationally predicted functions. The current version of CircFunBase documents more than 7000 manually curated functional circRNA entries, mainly including Homo sapiens, Mus musculus etc. CircFunBase provides visualized circRNA-miRNA interaction networks. In addition, a genome browser is provided to visualize the genome context of circRNAs. As a biological information platform for circRNAs, CircFunBase will contribute for circRNA studies and bridge the gap between circRNAs and their functions.

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