HisgAtlas 1.0: a human immunosuppression gene database | Zendy

Yuan Liu | Zendy; Mengqi He | Zendy; Dan Wang | Zendy; Lihong Diao | Zendy; Jinying Liu | Zendy; Tang Li | Zendy; Shuzhen Guo | Zendy; Fuchu He | Zendy; Dong Li | Zendy

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HisgAtlas 1.0: a human immunosuppression gene database

Author(s) -

Yuan Liu,

Mengqi He,

Dan Wang,

Lihong Diao,

Jinying Liu,

Tang Li,

Shuzhen Guo,

Fuchu He,

Dong Li

Publication year - 2017

Publication title -

database

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.406

H-Index - 62

ISSN - 1758-0463

DOI - 10.1093/database/bax094

Subject(s) - immunosuppression , computer science , database , gene , computational biology , world wide web , information retrieval , biology , genetics , immunology

Immunosuppression is body's state in which the activation or efficacy of immune system is weakened. It is associated with a wide spectrum of human diseases. In the last two decades, tremendous efforts have been made to elucidate the mechanism of hundreds of immunosuppression genes. Immunosuppression genes could be valuable drug targets or biomarkers for the immunotherapeutic treatment of different diseases. However, the information of all previously identified immunosuppression genes is dispersed in thousands of publications. Here, we provide the HisgAtlas database that collects 995 previously identified human immunosuppression genes using text mining and manual curation. We believe HisgAtlas will be a valuable resource to search human immunosuppression genes as well as to investigate their functions in further research. Database URL: http://biokb.ncpsb.org/HisgAtlas/.

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