P2Y12 antagonists and cardiac repair post-myocardial infarction: global and regional heart function analysis and molecular assessments in pigs | Zendy

Gemma Vilahur | Zendy; Manuel Gutiérrez | Zendy; Laura Casaní | Zendy; Carmen Lambert | Zendy; Guiomar Mendieta | Zendy; Soumaya BenAicha | Zendy; Antoni Capdevila | Zendy; Guillem PonsLladó | Zendy; Francesc Carreras | Zendy; Leif Carlsson | Zendy; Alberto Hidalgo | Zendy; Lina Badimón | Zendy

Open Access

P2Y12 antagonists and cardiac repair post-myocardial infarction: global and regional heart function analysis and molecular assessments in pigs

Author(s) -

Gemma Vilahur,

Manuel Gutiérrez,

Laura Casaní,

Carmen Lambert,

Guiomar Mendieta,

Soumaya BenAicha,

Antoni Capdevila,

Guillem PonsLladó,

Francesc Carreras,

Leif Carlsson,

Alberto Hidalgo,

Lina Badimón

Publication year - 2018

Publication title -

cardiovascular research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.774

H-Index - 219

eISSN - 1755-3245

pISSN - 0008-6363

DOI - 10.1093/cvr/cvy201

Subject(s) - ticagrelor , clopidogrel , medicine , cardiology , myocardial infarction , p2y12 , ejection fraction , aspirin , anesthesia , heart failure

P2Y12 antagonists are the standard in antiplatelet therapy but their potential effects on functional myocardial recovery and cardioprotection post-myocardial infarction (MI) are unknown. We investigated in a preclinical model of MI whether ticagrelor and clopidogrel differently affect cardiac repair post-MI.

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