Geranylgeranyl pyrophosphate synthase facilitates the organization of cardiomyocytes during mid-gestation through modulating protein geranylgeranylation in mouse heart | Zendy

Zhong Chen | Zendy; Na Xu | Zendy; Danyang Chong | Zendy; Shan Guan | Zendy; Jiang Chen | Zendy; Zhongzhou Yang | Zendy; Chaojun Li | Zendy

Open Access

Geranylgeranyl pyrophosphate synthase facilitates the organization of cardiomyocytes during mid-gestation through modulating protein geranylgeranylation in mouse heart

Author(s) -

Zhong Chen,

Na Xu,

Danyang Chong,

Shan Guan,

Jiang Chen,

Zhongzhou Yang,

Chaojun Li

Publication year - 2018

Publication title -

cardiovascular research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.774

H-Index - 219

eISSN - 1755-3245

pISSN - 0008-6363

DOI - 10.1093/cvr/cvy042

Subject(s) - geranylgeranylation , biology , cytoarchitecture , microbiology and biotechnology , biochemistry , anatomy , prenylation , enzyme

With the maturation of placenta, ventricular chamber maturation enhances cardiac contractile performance to adapt to the metabolic demand of growing embryo. The organization of cardiomyocytes is required for the morphological remodelling in ventricular chamber maturation. However, the mechanism governing the establishment of cardiac cytoarchitecture during ventricular chamber maturation is still poorly studied.

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