Patient-derived models link re-entrant driver localization in atrial fibrillation to fibrosis spatial pattern
Author(s) -
Sohail Zahid,
Hubert Cochet,
Patrick M. Boyle,
Erica L. Schwarz,
Kaitlyn N. Whyte,
Edward J. Vigmond,
Rémi Dubois,
Mélèze Hocini,
Michel Haı̈ssaguerre,
Pierre Jaı̈s,
Natalia A. Trayanova
Publication year - 2016
Publication title -
cardiovascular research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.774
H-Index - 219
eISSN - 1755-3245
pISSN - 0008-6363
DOI - 10.1093/cvr/cvw073
Subject(s) - atrial fibrillation , fibrosis , medicine , cardiology
The mechanisms underlying persistent atrial fibrillation (AF) in patients with atrial fibrosis are poorly understood. The goal of this study was to use patient-derived atrial models to test the hypothesis that AF re-entrant drivers (RDs) persist only in regions with specific fibrosis patterns.
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