Open AccessDeficiency of IL-12p35 improves cardiac repair after myocardial infarction by promoting angiogenesis
Author(s) -
Xiaoyu Kan,
Yina Wu,
Youcai Ma,
Congcong Zhang,
Ping Li,
Lifei Wu,
Shuai Zhang,
Yulin Li,
Jie Du
Publication year - 2015
Publication title -
cardiovascular research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.774
H-Index - 219
eISSN - 1755-3245
pISSN - 0008-6363
DOI - 10.1093/cvr/cvv255
Subject(s) - angiogenesis , inflammation , chemokine , medicine , neovascularization , matrigel , myocardial infarction , biology , immunology
IL-12p35 is a pro-inflammatory cytokine that participates in a variety of inflammatory diseases. This study aimed to determine whether IL-12 regulates cardiac injury and repair following acute myocardial infarction (AMI) and investigate the underlying mechanisms.
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