Human epicardial adipose tissue has a specific transcriptomic signature depending on its anatomical peri-atrial, peri-ventricular, or peri-coronary location | Zendy

Bénédicte Gaborit | Zendy; Nicolas Venteclef | Zendy; Patricia Ancel | Zendy; Véronique Pelloux | Zendy; Vlad Gariboldi | Zendy; Pascal Leprince | Zendy; Julien Amour | Zendy; Stéphane N. Hatem | Zendy; Élisabeth Jouve | Zendy; Anne Dutour | Zendy; Karine Clément | Zendy

Open Access

Human epicardial adipose tissue has a specific transcriptomic signature depending on its anatomical peri-atrial, peri-ventricular, or peri-coronary location

Author(s) -

Bénédicte Gaborit,

Nicolas Venteclef,

Patricia Ancel,

Véronique Pelloux,

Vlad Gariboldi,

Pascal Leprince,

Julien Amour,

Stéphane N. Hatem,

Élisabeth Jouve,

Anne Dutour,

Karine Clément

Publication year - 2015

Publication title -

cardiovascular research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.774

H-Index - 219

eISSN - 1755-3245

pISSN - 0008-6363

DOI - 10.1093/cvr/cvv208

Subject(s) - adipose tissue , atrial fibrillation , adipokine , transcriptome , medicine , coronary artery disease , peri , cardiology , endocrinology , biology , gene , gene expression , insulin resistance , obesity , genetics

Human epicardial adipose tissue (EAT) is a visceral and perivascular fat that has been shown to act locally on myocardium, atria, and coronary arteries. Its abundance has been linked to coronary artery disease (CAD) and atrial fibrillation. However, its physiological function remains highly debated. The aim of this study was to determine a specific EAT transcriptomic signature, depending on its anatomical peri-atrial (PA), peri-ventricular (PV), or peri-coronary location.

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