Open AccessOestrogen enhances cardiotoxicity induced by Sunitinib by regulation of drug transport and metabolism
Author(s) -
Pamela A. Harvey,
Leslie A. Leinwand
Publication year - 2015
Publication title -
cardiovascular research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.774
H-Index - 219
eISSN - 1755-3245
pISSN - 0008-6363
DOI - 10.1093/cvr/cvv152
Subject(s) - sunitinib , cardiotoxicity , tyrosine kinase , tyrosine kinase inhibitor , pharmacology , biology , aromatase , endocrinology , medicine , toxicity , signal transduction , microbiology and biotechnology , cancer , breast cancer
To define the molecular mechanisms of cardiotoxicity induced by Sunitinib and to identify the role of biological sex in modulating toxicity.
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