Toll-interacting protein (Tollip) negatively regulates pressure overload-induced ventricular hypertrophy in mice | Zendy

Yi Liu | Zendy; Xiao-Li Jiang | Zendy; Yu Liu | Zendy; ZhiGang She | Zendy; Yan Zhang | Zendy; Rui Zhang | Zendy; Yingjie Chen | Zendy; Qinglin Yang | Zendy; Xiaodong Zhang | Zendy; GuoChang Fan | Zendy; Hongliang Li | Zendy

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Toll-interacting protein (Tollip) negatively regulates pressure overload-induced ventricular hypertrophy in mice

Author(s) -

Yi Liu,

Xiao-Li Jiang,

Yu Liu,

ZhiGang She,

Yan Zhang,

Rui Zhang,

Yingjie Chen,

Qinglin Yang,

Xiaodong Zhang,

GuoChang Fan,

Hongliang Li

Publication year - 2013

Publication title -

cardiovascular research

Language(s) - Uncategorized

Resource type - Journals

SCImago Journal Rank - 2.774

H-Index - 219

eISSN - 1755-3245

pISSN - 0008-6363

DOI - 10.1093/cvr/cvt232

Subject(s) - pressure overload , muscle hypertrophy , regulator , microbiology and biotechnology , medicine , biology , endocrinology , cardiac hypertrophy , gene , biochemistry

Toll-interacting protein (Tollip) is a critical regulator of the Toll-like receptor-mediated signalling pathway. However, the role of Tollip in chronic pressure overload-induced cardiac hypertrophy remains unclear. This study aimed to determine the functional significance of Tollip in the regulation of aortic banding-induced cardiac remodelling and its underlying mechanisms.

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