Aerobic interval training attenuates remodelling and mitochondrial dysfunction in the post-infarction failing rat heart | Zendy

Jasenka Kraljević | Zendy; Jasna Marinović | Zendy; Danijel Pravdić | Zendy; Petra Zubin | Zendy; Željko Dujić | Zendy; Ulrik Wisløff | Zendy; Marko Ljubković | Zendy

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Aerobic interval training attenuates remodelling and mitochondrial dysfunction in the post-infarction failing rat heart

Author(s) -

Jasenka Kraljević,

Jasna Marinović,

Danijel Pravdić,

Petra Zubin,

Željko Dujić,

Ulrik Wisløff,

Marko Ljubković

Publication year - 2013

Publication title -

cardiovascular research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.774

H-Index - 219

eISSN - 1755-3245

pISSN - 0008-6363

DOI - 10.1093/cvr/cvt080

Subject(s) - cardiology , medicine , interval training , high intensity interval training , myocardial infarction , heart failure

Following a large myocardial infarction (MI), remaining viable muscle often undergoes pathological remodelling and progresses towards chronic heart failure. Mitochondria may also be affected by this process and, due to their functional importance, likely contribute to the progression of the disease. Aerobic interval training (AIT) has been shown effective in diminishing pathological myocardial transformation, but the effects of AIT on mitochondrial function in hearts undergoing remodelling are not known.

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