Induction of oxidative stress by oxidized LDL via meprinα-activated epidermal growth factor receptor in macrophages
Author(s) -
Pan Gao,
Xiaomei Wang,
Dei-hui Qian,
Ze-Xue Qin,
Jun Jin,
Qiang Xu,
QiaoYing Yuan,
Xuejun Li,
LiangYi Si
Publication year - 2012
Publication title -
cardiovascular research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.774
H-Index - 219
eISSN - 1755-3245
pISSN - 0008-6363
DOI - 10.1093/cvr/cvs369
Subject(s) - transactivation , epidermal growth factor receptor , oxidative stress , reactive oxygen species , microbiology and biotechnology , chemistry , receptor , biology , cancer research , biochemistry , transcription factor , gene
The aim of this study was to explore meprinα-mediated transactivation of the epidermal growth factor receptor (EGFR) and reactive oxygen species (ROS) production in macrophages.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom