Lipidomic and metabolomic analyses reveal potential plasma biomarkers of early atheromatous plaque formation in hamsters | Zendy

Mariona Jové | Zendy; Victòria Ayala | Zendy; Omar RamírezNúñez | Zendy; José C. E. Serrano | Zendy; Anna Cassanyé | Zendy; Lluı́s Arola | Zendy; Antoni Caimari | Zendy; Josep M Del Bas-Prior | Zendy; Anna Crescenti | Zendy; Reinald Pamplona | Zendy; Manuel PorteroOtín | Zendy

Open Access

Lipidomic and metabolomic analyses reveal potential plasma biomarkers of early atheromatous plaque formation in hamsters

Author(s) -

Mariona Jové,

Victòria Ayala,

Omar RamírezNúñez,

José C. E. Serrano,

Anna Cassanyé,

Lluı́s Arola,

Antoni Caimari,

Josep M Del Bas-Prior,

Anna Crescenti,

Reinald Pamplona,

Manuel PorteroOtín

Publication year - 2012

Publication title -

cardiovascular research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.774

H-Index - 219

eISSN - 1755-3245

pISSN - 0008-6363

DOI - 10.1093/cvr/cvs368

Subject(s) - lipidome , lipidomics , metabolomics , metabolome , lipid metabolism , biology , biochemistry , chemistry , bioinformatics

Atherosclerosis is the main pathological process contributing to cardiovascular disease, with diet being the most important factor involved. Although the lipidome of atheromatous plaque has been studied previously, the use of comparative lipidomics and metabolomics in plasma in early atherogenesis could lead to the discovery of plasma biomarkers that allow not only disease prediction but also measurement of disease progression.

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