Protective role of vascular smooth muscle cell PPARγ in angiotensin II-induced vascular disease | Zendy

Chiara Marchesi | Zendy; Asia Rehman | Zendy; Yohann Rautureau | Zendy; Daniel Arthur Barata Kasal | Zendy; Marie Briet | Zendy; Avshalom Leibowitz | Zendy; Stefania Simeone | Zendy; Talin Ebrahimian | Zendy; Mário Fritsch Neves | Zendy; Stefan Offermanns | Zendy; Frank J. Gonzalez | Zendy; Pierre Paradis | Zendy; Ernesto L. Schiffrin | Zendy

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Protective role of vascular smooth muscle cell PPARγ in angiotensin II-induced vascular disease

Author(s) -

Chiara Marchesi,

Asia Rehman,

Yohann Rautureau,

Daniel Arthur Barata Kasal,

Marie Briet,

Avshalom Leibowitz,

Stefania Simeone,

Talin Ebrahimian,

Mário Fritsch Neves,

Stefan Offermanns,

Frank J. Gonzalez,

Pierre Paradis,

Ernesto L. Schiffrin

Publication year - 2012

Publication title -

cardiovascular research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.774

H-Index - 219

eISSN - 1755-3245

pISSN - 0008-6363

DOI - 10.1093/cvr/cvs362

Subject(s) - vascular smooth muscle , angiotensin ii , vascular disease , disease , medicine , endocrinology , cardiology , receptor , smooth muscle

Vascular peroxisome proliferator-activated receptor γ (PPARγ) activation improves vascular remodelling and endothelial function in hypertensive rodents. The goal of this study was to determine that vascular smooth muscle cell (VSMC) PPARγ exerts a vascular protective role beyond its metabolic effects.

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