Early repolarization in mice causes overestimation of ventricular activation time by the QRS duration | Zendy

Bastiaan J. Boukens | Zendy; Mark G. Hoogendijk | Zendy; Arie O. Verkerk | Zendy; André C. Linnenbank | Zendy; Peter van Dam | Zendy; Carol Ann Remme | Zendy; Jan W.T. Fiolet | Zendy; Tobias Opthof | Zendy; Vincent M. Christoffels | Zendy; Ruben Coronel | Zendy

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Early repolarization in mice causes overestimation of ventricular activation time by the QRS duration

Author(s) -

Bastiaan J. Boukens,

Mark G. Hoogendijk,

Arie O. Verkerk,

André C. Linnenbank,

Peter van Dam,

Carol Ann Remme,

Jan W.T. Fiolet,

Tobias Opthof,

Vincent M. Christoffels,

Ruben Coronel

Publication year - 2012

Publication title -

cardiovascular research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.774

H-Index - 219

eISSN - 1755-3245

pISSN - 0008-6363

DOI - 10.1093/cvr/cvs299

Subject(s) - qrs complex , repolarization , cardiology , medicine , electrocardiography , electrical conduction system of the heart , electrophysiology

Transgenic mice are frequently used to investigate the role of genes involved in cardiac conduction. The QRS duration calculated from the electrocardiogram (ECG) is a commonly used measure for ventricular conduction time. However, the relation between ventricular activation and QRS duration calculated from a mouse surface ECG is not well understood. We aim to relate ventricular activation and repolarization patterns with the mouse ECG.

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