EP 80317, a selective CD36 ligand, shows cardioprotective effects against post-ischaemic myocardial damage in mice | Zendy

Valérie L. Bessi | Zendy; Sébastien M. Labbé | Zendy; David N. Huynh | Zendy; Liliane Ménard | Zendy; Christian Jossart | Zendy; Maria Febbraio | Zendy; Brigitte Guérin | Zendy; M’hamed Bentourkia | Zendy; Roger Lecomte | Zendy; André C. Carpentier | Zendy; Huy Ong | Zendy; Sylvie Marleau | Zendy

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EP 80317, a selective CD36 ligand, shows cardioprotective effects against post-ischaemic myocardial damage in mice

Author(s) -

Valérie L. Bessi,

Sébastien M. Labbé,

David N. Huynh,

Liliane Ménard,

Christian Jossart,

Maria Febbraio,

Brigitte Guérin,

M’hamed Bentourkia,

Roger Lecomte,

André C. Carpentier,

Huy Ong,

Sylvie Marleau

Publication year - 2012

Publication title -

cardiovascular research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.774

H-Index - 219

eISSN - 1755-3245

pISSN - 0008-6363

DOI - 10.1093/cvr/cvs225

Subject(s) - cd36 , medicine , endocrinology , fatty acid , lipolysis , myocardial infarction , adipose tissue , ischemia , cardiac function curve , ejection fraction , cardiology , receptor , heart failure , chemistry , biochemistry

The CD36 receptor plays an important role in facilitating fatty acid transport to the heart. The present study aimed to assess whether EP 80317, a selective synthetic peptide ligand of CD36, is cardioprotective in a murine model of myocardial ischaemia and reperfusion (MI/R) injury.

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