MicroRNA-195 regulates vascular smooth muscle cell phenotype and prevents neointimal formation | Zendy

YungSong Wang | Zendy; Hay-Yan J. Wang | Zendy; YiChu Liao | Zendy; PeiChien Tsai | Zendy; KuChung Chen | Zendy; Hsin-Yun Cheng | Zendy; Ruey-Tay Lin | Zendy; Suh-Hang Hank Juo | Zendy

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MicroRNA-195 regulates vascular smooth muscle cell phenotype and prevents neointimal formation

Author(s) -

YungSong Wang,

Hay-Yan J. Wang,

YiChu Liao,

PeiChien Tsai,

KuChung Chen,

Hsin-Yun Cheng,

Ruey-Tay Lin,

Suh-Hang Hank Juo

Publication year - 2012

Publication title -

cardiovascular research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.774

H-Index - 219

eISSN - 1755-3245

pISSN - 0008-6363

DOI - 10.1093/cvr/cvs223

Subject(s) - neointima , vascular smooth muscle , microrna , cdc42 , phenotypic switching , microbiology and biotechnology , calponin , neointimal hyperplasia , cell growth , biology , cancer research , medicine , signal transduction , stent , gene , restenosis , actin , smooth muscle , biochemistry

Proliferation and migration of vascular smooth muscle cells (VSMCs) can cause atherosclerosis and neointimal formation. MicroRNAs have been shown to regulate cell proliferation and phenotype transformation. We discovered abundant expression of microRNA-195 in VSMCs and conducted a series of studies to identify its function in the cardiovascular system.

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