Impaired sonic hedgehog pathway contributes to cardiac dysfunction in type 1 diabetic mice with myocardial infarction | Zendy

Qing Xiao | Zendy; Ning Hou | Zendy; Yanping Wang | Zendy; Lishan He | Zendy; Yanhua He | Zendy; Guiping Zhang | Zendy; Yi Quan | Zendy; Shiming Liu | Zendy; Minsheng Chen | Zendy; Jiandong Luo | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Impaired sonic hedgehog pathway contributes to cardiac dysfunction in type 1 diabetic mice with myocardial infarction

Author(s) -

Qing Xiao,

Ning Hou,

Yanping Wang,

Lishan He,

Yanhua He,

Guiping Zhang,

Yi Quan,

Shiming Liu,

Minsheng Chen,

Jiandong Luo

Publication year - 2012

Publication title -

cardiovascular research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.774

H-Index - 219

eISSN - 1755-3245

pISSN - 0008-6363

DOI - 10.1093/cvr/cvs216

Subject(s) - sonic hedgehog , gli1 , medicine , endocrinology , streptozotocin , cardiac function curve , myocardial infarction , diabetes mellitus , hedgehog signaling pathway , heart failure , biology , signal transduction , biochemistry

The incidence and mortality of myocardial infarction (MI) in diabetic patients are higher than in non-diabetic patients; however, the mechanisms by which diabetes results in cardiac dysfunction are poorly understood. The present study tested the hypothesis that an impaired sonic hedgehog (Shh) pathway contributes to cardiac dysfunction in type 1 diabetic mice with MI.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research