Disease characterization using LQTS-specific induced pluripotent stem cells | Zendy

Toru Egashira | Zendy; Shinsuke Yuasa | Zendy; Tomoyuki Suzuki | Zendy; Yoshiyasu Aizawa | Zendy; Hiroyuki Yamakawa | Zendy; Tomohiro Matsuhashi | Zendy; Yohei Ohno | Zendy; Shugo Tohyama | Zendy; Shinichiro Okata | Zendy; Tomohisa Seki | Zendy; Yusuke Kuroda | Zendy; Kojiro Yae | Zendy; Hisayuki Hashimoto | Zendy; Tomofumi Tanaka | Zendy; Fumiyuki Hattori | Zendy; Toshiaki Sato | Zendy; Shunichiro Miyoshi | Zendy; Seiji Takatsuki | Zendy; Mitsushige Murata | Zendy; Junko Kurokawa | Zendy; Tetsushi Furukawa | Zendy; Naomasa Makita | Zendy; Takeshi Aiba | Zendy; Wataru Shimizu | Zendy; Minoru Horie | Zendy; Kaichiro Kamiya | Zendy; Itsuo Kodama | Zendy; Satoshi Ogawa | Zendy; Keiichi Fukuda | Zendy

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Disease characterization using LQTS-specific induced pluripotent stem cells

Author(s) -

Toru Egashira,

Shinsuke Yuasa,

Tomoyuki Suzuki,

Yoshiyasu Aizawa,

Hiroyuki Yamakawa,

Tomohiro Matsuhashi,

Yohei Ohno,

Shugo Tohyama,

Shinichiro Okata,

Tomohisa Seki,

Yusuke Kuroda,

Kojiro Yae,

Hisayuki Hashimoto,

Tomofumi Tanaka,

Fumiyuki Hattori,

Toshiaki Sato,

Shunichiro Miyoshi,

Seiji Takatsuki,

Mitsushige Murata,

Junko Kurokawa,

Tetsushi Furukawa,

Naomasa Makita,

Takeshi Aiba,

Wataru Shimizu,

Minoru Horie,

Kaichiro Kamiya,

Itsuo Kodama,

Satoshi Ogawa,

Keiichi Fukuda

Publication year - 2012

Publication title -

cardiovascular research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.774

H-Index - 219

eISSN - 1755-3245

pISSN - 0008-6363

DOI - 10.1093/cvr/cvs206

Subject(s) - induced pluripotent stem cell , long qt syndrome , embryoid body , medicine , embryonic stem cell , somatic cell , pharmacology , qt interval , biology , genetics , gene

Long QT syndrome (LQTS) is an inheritable and life-threatening disease; however, it is often difficult to determine disease characteristics in sporadic cases with novel mutations, and more precise analysis is necessary for the successful development of evidence-based clinical therapies. This study thus sought to better characterize ion channel cardiac disorders using induced pluripotent stem cells (iPSCs).

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