Open AccessOverexpression of microRNA-1 impairs cardiac contractile function by damaging sarcomere assembly
Author(s) -
Jing Ai,
Rong Zhang,
Xu Gao,
Huifang Niu,
Ning Wang,
Yi Xu,
Yue Li,
Ning Ma,
Lihua Sun,
Zhenwei Pan,
Weimin Li,
Baofeng Yang
Publication year - 2012
Publication title -
cardiovascular research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.774
H-Index - 219
eISSN - 1755-3245
pISSN - 0008-6363
DOI - 10.1093/cvr/cvs196
Subject(s) - sarcomere , microrna , function (biology) , microbiology and biotechnology , cardiac function curve , cardiology , myocyte , medicine , biology , heart failure , genetics , gene
The purpose of the present study was to evaluate the effects of overexpression of microRNA-1 (miR-1) on cardiac contractile function and the potential molecular mechanisms.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom