Sources of cells that contribute to atherosclerotic intimal calcification: an in vivo genetic fate mapping study | Zendy

Veeik | Zendy; Elizabeth M. Leaf | Zendy; Jie Hu | Zendy; Hsueh-Ying Yang | Zendy; Ngoc B. Nguyen | Zendy; Cecilia M. Giachelli | Zendy; Mei Y. Speer | Zendy

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Sources of cells that contribute to atherosclerotic intimal calcification: an in vivo genetic fate mapping study

Author(s) -

Veeik,

Elizabeth M. Leaf,

Jie Hu,

Hsueh-Ying Yang,

Ngoc B. Nguyen,

Cecilia M. Giachelli,

Mei Y. Speer

Publication year - 2012

Publication title -

cardiovascular research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.774

H-Index - 219

eISSN - 1755-3245

pISSN - 0008-6363

DOI - 10.1093/cvr/cvs126

Subject(s) - bone marrow , calcification , biology , transdifferentiation , pathology , progenitor cell , stem cell , microbiology and biotechnology , immunology , medicine

Vascular cartilaginous metaplasia and calcification are common in patients with atherosclerosis. However, sources of cells contributing to the development of this complication are currently unknown. In this study, we ascertained the origin of cells that give rise to cartilaginous and bony elements in atherosclerotic vessels.

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