NecroX-5 prevents hypoxia/reoxygenation injury by inhibiting the mitochondrial calcium uniporter | Zendy

Vũ Thị Thu | Zendy; Hyoung Kyu Kim | Zendy; Lê Thành Long | Zendy; Sungryul Lee | Zendy; Tran My Hanh | Zendy; Tae Hee Ko | Zendy; Hye-Jin Heo | Zendy; Nari Kim | Zendy; Soon Ha Kim | Zendy; Kyung Soo Ko | Zendy; Byoung Doo Rhee | Zendy; Jin Han | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

NecroX-5 prevents hypoxia/reoxygenation injury by inhibiting the mitochondrial calcium uniporter

Author(s) -

Vũ Thị Thu,

Hyoung Kyu Kim,

Lê Thành Long,

Sungryul Lee,

Tran My Hanh,

Tae Hee Ko,

Hye-Jin Heo,

Nari Kim,

Soon Ha Kim,

Kyung Soo Ko,

Byoung Doo Rhee,

Jin Han

Publication year - 2012

Publication title -

cardiovascular research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.774

H-Index - 219

eISSN - 1755-3245

pISSN - 0008-6363

DOI - 10.1093/cvr/cvs122

Subject(s) - uniporter , mitochondrion , mitochondrial permeability transition pore , hypoxia (environmental) , pharmacology , oxidative stress , ischemia , calcium , ouabain , inner mitochondrial membrane , reactive oxygen species , chemistry , microbiology and biotechnology , medicine , biology , endocrinology , oxygen , biochemistry , cytosol , programmed cell death , apoptosis , organic chemistry , enzyme , sodium

Preservation of mitochondrial function is essential to limit myocardial damage in ischaemic heart disease. We examined the protective effects and mechanism of a new compound, NecroX-5, on rat heart mitochondria in a hypoxia/reoxygenation (HR) model.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research