Open AccessLoss of the miR-144/451 cluster impairs ischaemic preconditioning-mediated cardioprotection by targeting Rac-1
Author(s) -
Xiaohong Wang,
Hongyan Zhu,
Xiaowei Zhang,
Yong Liu,
Jing Chen,
Mario Medvedovic,
Hongliang Li,
Mitchell J. Weiss,
Xiaoping Ren,
GuoChang Fan
Publication year - 2012
Publication title -
cardiovascular research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.774
H-Index - 219
eISSN - 1755-3245
pISSN - 0008-6363
DOI - 10.1093/cvr/cvs096
Subject(s) - cardioprotection , ischemic preconditioning , ischemia , cardiology , medicine , myocardial infarction , pharmacology , chemistry
While a wealth of data has uncovered distinct microRNA (miR) expression alterations in hypertrophic and ischaemic/reperfused (I/R) hearts, little is known about miR regulation and response to ischaemic preconditioning (IPC).
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