Energy-preserving effects of IGF-1 antagonize starvation-induced cardiac autophagy | Zendy

Rodrigo Troncoso | Zendy; José M. Vicencio | Zendy; Valentina Parra | Zendy; Andriy Nemchenko | Zendy; Y. Kawashima | Zendy; Andrea del Campo | Zendy; Barbra Toro | Zendy; Pavan K. Battiprolu | Zendy; Pablo Aránguiz | Zendy; Mario Chiong | Zendy; Shoshana Yakar | Zendy; Thomas G. Gillette | Zendy; Joseph A. Hill | Zendy; E. Dale Abel | Zendy; Derek LeRoith | Zendy; Sergio Lavandero | Zendy

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Energy-preserving effects of IGF-1 antagonize starvation-induced cardiac autophagy

Author(s) -

Rodrigo Troncoso,

José M. Vicencio,

Valentina Parra,

Andriy Nemchenko,

Y. Kawashima,

Andrea del Campo,

Barbra Toro,

Pavan K. Battiprolu,

Pablo Aránguiz,

Mario Chiong,

Shoshana Yakar,

Thomas G. Gillette,

Joseph A. Hill,

E. Dale Abel,

Derek LeRoith,

Sergio Lavandero

Publication year - 2011

Publication title -

cardiovascular research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.774

H-Index - 219

eISSN - 1755-3245

pISSN - 0008-6363

DOI - 10.1093/cvr/cvr321

Subject(s) - autophagy , ampk , pi3k/akt/mtor pathway , cardioprotection , protein kinase b , programmed cell death , microbiology and biotechnology , biology , phosphorylation , mitochondrion , intracellular , protein kinase a , endocrinology , medicine , apoptosis , signal transduction , biochemistry , ischemia

Insulin-like growth factor 1 (IGF-1) is known to exert cardioprotective actions. However, it remains unknown if autophagy, a major adaptive response to nutritional stress, contributes to IGF-1-mediated cardioprotection.

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