Open AccessHypoxia-induced hyperreactivity of pulmonary arteries: role of cyclooxygenase-2, isoprostanes, and thromboxane receptors
Author(s) -
E Delannoy,
Arnaud Courtois,
Véronique FreundMichel,
Véronique Leblais,
Roger Marthan,
Bernard Müller
Publication year - 2009
Publication title -
cardiovascular research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.774
H-Index - 219
eISSN - 1755-3245
pISSN - 0008-6363
DOI - 10.1093/cvr/cvp292
Subject(s) - cyclooxygenase , endocrinology , medicine , thromboxane a2 , hypoxic pulmonary vasoconstriction , hypoxia (environmental) , prostacyclin , thromboxane , arachidonic acid , thromboxane a synthase , thromboxane receptor , prostaglandin h2 , prostanoid , prostaglandin , pulmonary hypertension , chemistry , receptor , biochemistry , platelet , enzyme , organic chemistry , oxygen
This study investigates the role of the cyclooxygenase (COX)/prostanoid pathway in chronic hypoxia-induced hyperreactivity of pulmonary arteries.
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