Open AccessSilencing TRPM7 promotes growth/proliferation and nitric oxide production of vascular endothelial cells via the ERK pathway
Author(s) -
Kōichi Inoue,
ZhiGang Xiong
Publication year - 2009
Publication title -
cardiovascular research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.774
H-Index - 219
eISSN - 1755-3245
pISSN - 0008-6363
DOI - 10.1093/cvr/cvp153
Subject(s) - trpm7 , mapk/erk pathway , microbiology and biotechnology , cell growth , small interfering rna , gene silencing , extracellular , transient receptor potential channel , chemistry , signal transduction , nitric oxide , kinase , biology , cell culture , transfection , receptor , biochemistry , endocrinology , genetics , gene
The presence and potential function of transient receptor potential melastatin 7 (TRPM7), a Ca2+-permeable non-selective cation channel of the TRP channel superfamily in human vascular endothelial cells, were examined.
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