A novel CXCR4 antagonist derived from human SDF-1β enhances angiogenesis in ischaemic mice
Author(s) -
Yi Tan,
Yan Li,
Jian Xiao,
Hongwei Shao,
Chuanlin Ding,
Gavin E. Arteel,
Keith A. Webster,
Jun Yan,
Hong Yu,
Lu Cai,
Xiaokun Li
Publication year - 2009
Publication title -
cardiovascular research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.774
H-Index - 219
eISSN - 1755-3245
pISSN - 0008-6363
DOI - 10.1093/cvr/cvp044
Subject(s) - angiogenesis , stromal cell derived factor 1 , cxc chemokine receptors , antagonist , cxcr4 antagonist , stromal cell , ischemia , cxcr4 , receptor antagonist , arteriogenesis , medicine , pharmacology , receptor , endocrinology , biology , chemokine , chemokine receptor , chemistry
The effects on angiogenesis of a novel CXC chemokine receptor 4 (CXCR4) antagonist, SDF-1betaP2G, derived from human stromal cell-derived factor-1beta (SDF-1beta), were examined in a model of hind limb ischaemia in mice.
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