Open AccessSalvianolic acid B protects human endothelial cells from oxidative stress damage: a possible protective role of glucose-regulated protein 78 induction
Author(s) -
Hongyan Wu,
Li Yh,
Yu-Shiang Lin,
Renheng Wang,
Yongbing Li,
Lu Tie,
Q.-L. Song,
D.-A. Guo,
Huidong Yu,
Xiaowei Li
Publication year - 2008
Publication title -
cardiovascular research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.774
H-Index - 219
eISSN - 1755-3245
pISSN - 0008-6363
DOI - 10.1093/cvr/cvn262
Subject(s) - atf4 , atf6 , unfolded protein response , microbiology and biotechnology , glucose regulated protein , endoplasmic reticulum , eif 2 kinase , viability assay , activating transcription factor , gene knockdown , umbilical vein , biology , apoptosis , kinase , chemistry , protein kinase a , biochemistry , cyclin dependent kinase 2 , in vitro
The purposes of the present study were to both evaluate the protective effects of Salvianolic acid B (Sal B) and to determine the possible molecular mechanisms by which Sal B protects endothelial cells from damage caused by oxidative stress.
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