Haeme oxygenase promotes progenitor cell mobilization, neovascularization, and functional recovery after critical hindlimb ischaemia in mice | Zendy

Jörn Tongers | Zendy; Joanne Knapp | Zendy; M. Korf | Zendy; Tibor Kempf | Zendy; Anne Limbourg | Zendy; Florian P. Limbourg | Zendy; Zhixiong Li | Zendy; Daniela Fraccarollo | Zendy; Johann Bauersachs | Zendy; Xu Han | Zendy; H. Drexler | Zendy; B. Fiedler | Zendy; Kai C. Wollert | Zendy

Open Access

Haeme oxygenase promotes progenitor cell mobilization, neovascularization, and functional recovery after critical hindlimb ischaemia in mice

Author(s) -

Jörn Tongers,

Joanne Knapp,

M. Korf,

Tibor Kempf,

Anne Limbourg,

Florian P. Limbourg,

Zhixiong Li,

Daniela Fraccarollo,

Johann Bauersachs,

Xu Han,

H. Drexler,

B. Fiedler,

Kai C. Wollert

Publication year - 2007

Publication title -

cardiovascular research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.774

H-Index - 219

eISSN - 1755-3245

pISSN - 0008-6363

DOI - 10.1093/cvr/cvm107

Subject(s) - hindlimb , progenitor cell , neovascularization , arteriogenesis , bone marrow , transplantation , angiogenesis , medicine , biology , endocrinology , pathology , stem cell , microbiology and biotechnology

Neovascularization is an important element of long-term functional recovery during chronic ischaemia. We postulated that haeme oxygenase (HO) is required for progenitor cell recruitment, neovascularization, and blood flow recovery after critical hindlimb ischaemia (HLI).

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