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Protein kinase C promotes angiogenic activity of human endothelial cells via induction of vascular endothelial growth factor
Author(s) -
Hui Xu,
Petra Czerwinski,
Marcus Hortmann,
H.-Y. Sohn,
Ulrich Förstermann,
Huige Li
Publication year - 2007
Publication title -
cardiovascular research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.774
H-Index - 219
eISSN - 1755-3245
pISSN - 0008-6363
DOI - 10.1093/cvr/cvm085
Subject(s) - protein kinase c , matrigel , angiogenesis , umbilical vein , vascular endothelial growth factor , pkc alpha , gene knockdown , microbiology and biotechnology , vascular endothelial growth factor a , signal transduction , endothelial stem cell , chemistry , biology , cell culture , cancer research , in vitro , biochemistry , vegf receptors , genetics
Protein kinase C (PKC) plays an important role in the regulation of angiogenesis. However, downstream targets of PKC in endothelial cells are poorly defined.

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