Activation of fractalkine/CX3CR1 by vascular endothelial cells induces angiogenesis through VEGF-A/KDR and reverses hindlimb ischaemia | Zendy

JinSook Ryu | Zendy; C.-W. Lee | Zendy; Ki Hwan Hong | Zendy; J.-A. Shin | Zendy; SungHoon Lim | Zendy; C.-S. Park | Zendy; Ju Hyun Shim | Zendy; KyungOk Nam | Zendy; KwiSook Choi | Zendy; YoungHoon Kim | Zendy; Ki Hoon Han | Zendy

Open Access

Activation of fractalkine/CX3CR1 by vascular endothelial cells induces angiogenesis through VEGF-A/KDR and reverses hindlimb ischaemia

Author(s) -

JinSook Ryu,

C.-W. Lee,

Ki Hwan Hong,

J.-A. Shin,

SungHoon Lim,

C.-S. Park,

Ju Hyun Shim,

KyungOk Nam,

KwiSook Choi,

YoungHoon Kim,

Ki Hoon Han

Publication year - 2007

Publication title -

cardiovascular research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.774

H-Index - 219

eISSN - 1755-3245

pISSN - 0008-6363

DOI - 10.1093/cvr/cvm067

Subject(s) - angiogenesis , neovascularization , cx3cr1 , kinase insert domain receptor , vascular endothelial growth factor , cancer research , vascular endothelial growth factor a , biology , chemokine , immunology , chemokine receptor , inflammation , vegf receptors

The present study investigated the detailed mechanism by which fractalkine (Fkn), a CX3C chemokine, induces angiogenesis and its functional implication in alleviating ischaemia in vivo.

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