Current Understanding of Sepsis | Zendy

R P Wenzel | Zendy; Michael R. Pinsky | Zendy; Richard J. Ulevitch | Zendy; L. Young | Zendy

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Current Understanding of Sepsis

Author(s) -

R P Wenzel,

Michael R. Pinsky,

Richard J. Ulevitch,

L. Young

Publication year - 1996

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/clinids/22.3.407

Subject(s) - medicine , septic shock , sepsis , bacteremia , intensive care medicine , shock (circulatory) , blood culture , cause of death , pediatrics , disease , antibiotics , microbiology and biotechnology , biology

Sepsis and septic shock represent the thirteenth leading cause of death in the United States. It has been estimated that there are 500,000 new episodes each year, with an associated crude mortality of 35% [1]. Over the last 4 decades the age-adjusted mortality has climbed steadily from 0.5 to 7 per 100,000 episodes [2]. Approximately one-third to one-half of patients who are septic have culture-positive blood, and much of our understanding of this clinical syndrome derives from studies of nosocomial bacteremia and candidemia.

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