Effect of Plasma Replacement Therapy on Determinations of Urine Protein Concentration | Zendy

Clara Peña | Zendy; Cecília Martínez-Brú | Zendy; R. Homs | Zendy; Teresa Planella | Zendy; Mariano Cortés | Zendy

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Effect of Plasma Replacement Therapy on Determinations of Urine Protein Concentration

Author(s) -

Clara Peña,

Cecília Martínez-Brú,

R. Homs,

Teresa Planella,

Mariano Cortés

Publication year - 1998

Publication title -

clinical chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.705

H-Index - 218

eISSN - 1530-8561

pISSN - 0009-9147

DOI - 10.1093/clinchem/44.2.359

Subject(s) - turbidimetry , nephelometry , urine , chemistry , chromatography , albumin , pyrogallol , urinary system , blood proteins , antibody , biochemistry , immunology , medicine

Total protein concentration in urine is currently analyzed in our laboratory by a colorimetric method—Pyrogallol Red (PR)–molybdate complex (1)—adapted to a Cobas Integra analyzer (Cobas Integra Total Protein Urine/CSF 07.5723.3; Roche). We quantify specific urinary proteins by the following immunochemical methods: turbidimetry for urinary albumin (Cobas Integra) and nephelometry for IgG, α1-microglobulin, and light chains of immunoglobulins (BNAII; Behring).We recently observed discrepancies between results obtained for some urine samples, in that the total protein concentration was increased and did …

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