Acute kidney injury pathology and pathophysiology: a retrospective review | Zendy

Joseph P. Gaut | Zendy; Helen Liapis | Zendy

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Acute kidney injury pathology and pathophysiology: a retrospective review

Author(s) -

Joseph P. Gaut,

Helen Liapis

Publication year - 2020

Publication title -

clinical kidney journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.033

H-Index - 40

eISSN - 2048-8513

pISSN - 2048-8505

DOI - 10.1093/ckj/sfaa142

Subject(s) - medicine , acute kidney injury , kidney disease , intensive care medicine , renal function , renal pathology , pathophysiology , disease , kidney , pathology

Acute kidney injury (AKI) is the clinical term used for decline or loss of renal function. It is associated with chronic kidney disease (CKD) and high morbidity and mortality. However, not all causes of AKI lead to severe consequences and some are reversible. The underlying pathology can be a guide for treatment and assessment of prognosis. The Kidney Disease: Improving Global Outcomes guidelines recommend that the cause of AKI should be identified if possible. Renal biopsy can distinguish specific AKI entities and assist in patient management. This review aims to show the pathology of AKI, including glomerular and tubular diseases.

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