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Impact of the Introduction of Rotavirus Vaccine on Hospital Admissions for Diarrhea Among Children in Kenya: A Controlled Interrupted Time-Series Analysis
Author(s) -
Grieven P. Otieno,
Christian Bottomley,
Sammy Khagayi,
Ifedayo Adetifa,
Mwanajuma Ngama,
Richard Omore,
Billy Ogwel,
Betty E. Owor,
Godfrey Bigogo,
John B. Ochieng,
Clayton Onyango,
Jane Juma,
Jason M. Mwenda,
Collins Tabu,
Jacqueline E. Tate,
O. Yaw Addo,
Tuck Britton,
Umesh D. Parashar,
Robert F. Breiman,
Jennifer R. Verani,
D. James Nokes
Publication year - 2019
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/ciz912
Subject(s) - medicine , rotavirus vaccine , rotavirus , diarrhea , incidence (geometry) , pediatrics , confidence interval , population , vaccine efficacy , vaccination , environmental health , virology , physics , optics
Monovalent rotavirus vaccine, Rotarix (GlaxoSmithKline), was introduced in Kenya in July 2014 and is recommended to infants as oral doses at ages 6 and 10 weeks. A multisite study was established in 2 population-based surveillance sites to evaluate vaccine impact on the incidence of rotavirus-associated hospitalizations (RVHs).

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