The Severe Typhoid Fever in Africa Program: Study Design and Methodology to Assess Disease Severity, Host Immunity, and Carriage Associated With Invasive Salmonellosis
Author(s) -
Se Eun Park,
Trevor Toy,
Ligia María Cruz Espinoza,
Ursula Panzner,
Ondari D. Mogeni,
Justin Im,
Nimesh Poudyal,
Gi Deok Pak,
Hyeong-Won Seo,
Yun Chon,
Heidi SchüttGerowitt,
Vittal Mogasale,
Enusa Ramani,
Ayan Dey,
Ju Yeong Park,
JongHoon Kim,
Hye Jin Seo,
Hyon Jin Jeon,
Andrea Haselbeck,
Keriann Conway Roy,
William R MacWright,
Yaw AduSarkodie,
Ellis OwusuDabo,
Isaac Osei,
Michael Owusu,
Raphaël Rakotozandrindrainy,
Abdramane Soura,
Leon Parfait Kabore,
Mekonnen Teferi,
Iruka N. Okeke,
Aderemi Kehinde,
Oluwafemi Popoola,
Jan Jacobs,
Octavie Lunguya Metila,
Christian G. Meyer,
John A. Crump,
Sean C. Elias,
Calman A. MacLennan,
Christopher M. Parry,
Stephen Baker,
Eric D. Mintz,
Robert F. Breiman,
John D. Clemens,
Florian Marks
Publication year - 2019
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/ciz715
Subject(s) - typhoid fever , medicine , carriage , salmonella , vaccination , public health , immunology , virology , biology , nursing , pathology , bacteria , genetics
Invasive salmonellosis is a common community-acquired bacteremia in persons residing in sub-Saharan Africa. However, there is a paucity of data on severe typhoid fever and its associated acute and chronic host immune response and carriage. The Severe Typhoid Fever in Africa (SETA) program, a multicountry surveillance study, aimed to address these research gaps and contribute to the control and prevention of invasive salmonellosis.
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