Interleukin (IL)-1β and IL-10 Host Responses in Patients With Staphylococcus aureus Bacteremia Determined by Antimicrobial Therapy | Zendy

Cecilia Volk | Zendy; Sarah Burgdorf | Zendy; Graham Edwardson | Zendy; Victor Nizet | Zendy; George Sakoulas | Zendy; Warren E. Rose | Zendy

Open Access

Interleukin (IL)-1β and IL-10 Host Responses in Patients With Staphylococcus aureus Bacteremia Determined by Antimicrobial Therapy

Author(s) -

Cecilia Volk,

Sarah Burgdorf,

Graham Edwardson,

Victor Nizet,

George Sakoulas,

Warren E. Rose

Publication year - 2019

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciz686

Subject(s) - daptomycin , medicine , anakinra , bacteremia , staphylococcus aureus , nafcillin , antimicrobial , cefazolin , vancomycin , antibiotics , staphylococcal infections , microbiology and biotechnology , penicillin , biology , bacteria , disease , genetics

Patient interleukin (IL)-1β and IL-10 responses early in Staphylococcus aureus bacteremia (SaB) are associated with bacteremia duration and mortality. We hypothesized that these responses vary depending on antimicrobial therapy, with particular interest in whether the superiority of β-lactams links to key cytokine pathways.

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